2024
Yu, M., Yin, N., Feng, B., Gao, P., Yu, K., Liu, H., Liu, H., Li, Y., Ginnard, O. Z., Conde, K. M., Wang, M., Fang, X., Tu, L., Bean, J. C., Liu, Q., Deng, Y., Yang, Y., Han, J., Jossy, S. V., & Burt, M. L. (2024). Identification of an ionic mechanism for ERα-mediated rapid excitation in neurons. Science Advances, 10(40). https://doi.org/10.1126/sciadv.adp0696
Kim, D. M., Lee, J. H., Pan, Q., Han, H. W., Shen, Z., Eshghjoo, S., Wu, C.-S., Yang, W., Noh, J. Y., Threadgill, D. W., Guo, S., Wright, G., Alaniz, R., & Sun, Y. (2024). Nutrient-sensing growth hormone secretagogue receptor in macrophage programming and meta-inflammation. Molecular Metabolism, 79, 101852. https://doi.org/10.1016/j.molmet.2023.101852
Pan, Q., Ai, W., & Guo, S. (2024). TGF-β1 Signaling Impairs Metformin Action on Glycemic Control. International Journal of Molecular Sciences, 25(4), 2424–2424. https://doi.org/10.3390/ijms25042424
Yang, W., Jiang, W., Liao, W., Yan, H., Ai, W., Pan, Q., Brashear, W. A., Xu, Y., He, L., & Guo, S. (2024). An estrogen receptor α-derived peptide improves glucose homeostasis during obesity. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-47687-6
Yang, W., Arora, M., Han, H. W., Jiang, W., Kim, D. M., Ai, W., Pan, Q., Ravi, V., Brashear, W. A., Sun, Y., & Guo, S. (2024). ZnPP‐laden nanoparticles improve glucose homeostasis and chronic inflammation during obesity. British Journal of Pharmacology, 181(16), 2886–2904. https://doi.org/10.1111/bph.16356
Han, H. W., Pradhan, G., Villarreal, D., Kim, D. M., Jain, A., Akhilesh Gaharwar, Tian, Y., Guo, S., & Sun, Y. (2024). GHSR Deletion in β-Cells of Male Mice: Ineffective in Obesity, but Effective in Protecting against Streptozotocin-Induced β-Cell Injury in Aging. Nutrients, 16(10), 1464–1464. https://doi.org/10.3390/nu16101464
Pan, Q., Gao, M., Kim, D., Ai, W., Yang, W., Jiang, W., Brashear, W., Dai, Y., Li, S., Sun, Y., Qi, Y., & Guo, S. (2024). Hepatocyte FoxO1 Deficiency Protects From Liver Fibrosis via Reducing Inflammation and TGF-β1-mediated HSC Activation. CMGH, 17(1), 41–58. https://doi.org/10.1016/j.jcmgh.2023.08.013
Yang, W., Guo, J., & Guo, S. (2023). Insulin Resistance in Obesity. Springer EBooks, 405–427. https://doi.org/10.1007/978-3-031-40116-9_28
2023
Yang, W., Kim, D. M., Jiang, W., Ai, W., Pan, Q., Rahman, S., Cai, J. J., Brashear, W. A., Sun, Y., & Guo, S. (2023). Suppression of FOXO1 attenuates inflamm-aging and improves liver function during aging. Aging cell, e13968. Advance online publication. https://doi.org/10.1111/acel.13968
Yang, W., Liao, W., Li, X., Ai, W., Pan, Q., Shen, Z., ... & Guo, S. (2023). Hepatic p38α MAPK controls gluconeogenesis via FOXO1 phosphorylation at S273 during glucagon signalling in mice. Diabetologia, 66(7), 1322-1339.
Pan, Q., Ai, W., Chen, Y., Kim, D. M., Shen, Z., Yang, W., ... & Guo, S. (2023). Reciprocal regulation of hepatic TGF-β1 and Foxo1 controls gluconeogenesis and energy expenditure. Diabetes, db230180.
YANG, W., ARORA, M., HAN, H., JIANG, W., DA KIM, M. I., AI, W., ... & GUO, S. (2023). 1508-P: ZnPP-Laden Nanoparticles Improve Glucose Homeostasis and Chronic Inflammation during Obesity. Diabetes, 72(Supplement_1).
Chen, Y., Pan, Q., Liao, W., Ai, W., Yang, S., & Guo, S. (2023). Transcription factor Foxo1 mediates TGF-β1-induced apoptosis in hepatocytes. The American Journal of Pathology.
Pan, Q., Gao, M., Kim, D., Ai, W., Yang, W., Jiang, W., ... & Guo, S. (2023). Hepatocyte FoxO1 Deficiency Protects From Liver Fibrosis via Reducing Inflammation and TGF-β1-mediated HSC Activation. Cellular and Molecular Gastroenterology and Hepatology.
2022
Peng, J., Qin, C., Ramatchandirin, B., Pearah, A., Guo, S., Hussain, M., ... & He, L. (2022). Activation of the canonical ER stress IRE1–XBP1 pathway by insulin regulates glucose and lipid metabolism. Journal of Biological Chemistry, 298(9).
Chen, J., Tang, S., Ke, S., Cai, J. J., Osorio, D., Golovko, A., ... & Tian, Y. (2022). Ablation of long noncoding RNA MALAT1 activates antioxidant pathway and alleviates sepsis in mice. Redox Biology, 54, 102377.
Yan, H., Yang, W., Zhou, F., Pan, Q., Allred, K., Allred, C., ... & Guo, S. (2022). Estrogen protects cardiac function and energy metabolism in dilated cardiomyopathy induced by loss of cardiac IRS1 and IRS2. Circulation: Heart Failure, 15(6), e008758.
Yang, W., Yan, H., Zhou, F., Pan, Q., Allred, K., Allred, C., ... & Guo, S. (2022). Sexual Dimorphism in Control of Heart Failure in Insulin Resistance. The FASEB Journal, 36.
Pan, Q., Gao, M., Ai, W., Shen, Z., Yang, W., Sun, Y., ... & Guo, S. (2022). FoxO1 Promotes Liver Fibrosis through TGF‐β1 mediated Hepatic Stellate Cell Activation. The FASEB Journal, 36.
Pradhan, G., Lee, J. H., Wu, C. S., Wang, H., Lin, L., Donti, T., ... & Samson, S. L. (2022). Mechanistic Investigation of GHS-R Mediated Glucose-Stimulated Insulin Secretion in Pancreatic Islets. Biomolecules 2022, 12, 407.
Cao, W., Geng, Z. Z., Wang, N., Pan, Q., Guo, S., Xu, S., ... & Liu, W. R. (2022). Cover Picture: A Reversible Chemogenetic Switch for Chimeric Antigen Receptor T Cells (Angew. Chem. Int. Ed. 10/2022). Angewandte Chemie International Edition, 61(10), e202201860.
Cao, W., Geng, Z. Z., Wang, N., Pan, Q., Guo, S., Xu, S., ... & Liu, W. R. (2022). Titelbild: A Reversible Chemogenetic Switch for Chimeric Antigen Receptor T Cells (Angew. Chem. 10/2022). Angewandte Chemie, 134(10), e202201860.
Peng, J., Ramatchandirin, B., Wang, Y., Pearah, A., Namachivayam, K., Wolf, R. M., ... & He, L. (2022). The P300 acetyltransferase inhibitor C646 promotes membrane translocation of insulin receptor protein substrate and interaction with the insulin receptor. Journal of Biological Chemistry, 298(3).
Cao, W., Geng, Z. Z., Wang, N., Pan, Q., Guo, S., Xu, S., ... & Liu, W. R. (2022). A reversible chemogenetic switch for chimeric antigen receptor T cells. Angewandte Chemie, 134(10), e202109550.
2021
Wei, Q., Lee, J. H., Wu, C. S., Zang, Q. S., Guo, S., Lu, H. C., & Sun, Y. (2021). Metabolic and inflammatory functions of cannabinoid receptor type 1 are differentially modulated by adiponectin. World Journal of Diabetes, 12(10), 1750.
Cao, W., Geng, Z. Z., Wang, N., Pan, Q., Guo, S., Xu, S., ... & Liu, W. R. (2021). A Recurring Chemogenetic Switch for Chimeric Antigen Receptor T Cells. bioRxiv, 2021-08.
Guo, X., Li, X., Yang, W., Liao, W., Shen, J. Z., Ai, W., ... & Guo, S. (2021). Metformin targets Foxo1 to control glucose homeostasis. Biomolecules, 11(6), 873.
Pradhan, G., Wu, C. S., Villarreal, D., Lee, J. H., Han, H. W., Gaharwar, A., ... & Sun, Y. (2021). β cell GHS-R regulates insulin secretion and sensitivity. International Journal of Molecular Sciences, 22(8), 3950.
Lee, J. H., Lin, L., Ye, X., Wolfrum, C., Chen, Y., Guo, S., & Sun, Y. (2021). GHS-R in brown fat potentiates differential thermogenic responses under metabolic and thermal stresses. PloS one, 16(4), e0249420.
Liao, W., Yang, W., Shen, Z., Ai, W., Pan, Q., Sun, Y., & Guo, S. (2021). Heme oxygenase-1 regulates ferrous iron and Foxo1 in control of hepatic gluconeogenesis. Diabetes, 70(3), 696-709.
Shen, J. Z., Wu, G., & Guo, S. (2021). Amino acids in autophagy: Regulation and function. Amino Acids in Nutrition and Health: Amino Acids in Gene Expression, Metabolic Regulation, and Exercising Performance, 51-66.
2020
Zhao, L. G., Li, P. L., Dai, Y., Deng, J. L., Shan, M. Y., Chen, B., ... & Xu, Z. H. (2020). Mibefradil Alleviates High-Glucose–Induced Cardiac Hypertrophy by Inhibiting PI3K/Akt/MTOR-Mediated Autophagy. Journal of Cardiovascular Pharmacology, 76(2), 246-254.
Liao, W., Yang, W., Pan, Q., Shen, Z., Ai, W., & GUO, S. (2020). 1718-P: Heme Oxygenase-1 Promotes Hepatic Glucose Production via Increasing the Intracellular Ferrous Iron. Diabetes, 69(Supplement_1).
Ai, W., Liao, W., Pan, Q., Yang, W., Shen, Z., GUO, S., & Chen, Y. (2020). 1723-P: Transcription Factor Foxo1 Mediates TGF-ß1-Induced Apoptosis in Primary Hepatocytes. Diabetes, 69(Supplement_1).
Wu, C. S., Wei, Q., Wang, H., Kim, D. M., Balderas, M., Wu, G., ... & Sun, Y. (2020). Protective effects of ghrelin on fasting-induced muscle atrophy in aging mice. The Journals of Gerontology: Series A, 75(4), 621-630.
Li, X., Chan, L. W., Li, X., Liu, C., Yang, G., Gao, J., ... & Yang, S. (2020). Obesity-induced regulator of calcineurin 1 overexpression leads to β-cell failure through mitophagy pathway inhibition. Antioxidants & redox signaling, 32(7), 413-428.
2019
Zhou, J., Li, H., Cai, Y., Ma, L., Matthews, D., Lu, B., ... & Wu, C. (2019). Mice lacking adenosine 2A receptor reveal increased severity of MCD-induced NASH. Journal of Endocrinology, 243(3), 199-209.
Wang, Y., An, H., Liu, T., Qin, C., Sesaki, H., Guo, S., ... & He, L. (2019). Metformin improves mitochondrial respiratory activity through activation of AMPK. Cell reports, 29(6), 1511-1523.
Villarreal, D., Pradhan, G., Wu, C. S., Allred, C. D., Guo, S., & Sun, Y. (2019). A simple high efficiency protocol for pancreatic islet isolation from mice. JoVE (Journal of Visualized Experiments), (150), e57048.
Liao, X., Song, L., Zeng, B., Liu, B., Qiu, Y., Qu, H., ... & Zheng, H. (2019). Alteration of gut microbiota induced by DPP-4i treatment improves glucose homeostasis. EBioMedicine, 44, 665-674.
SHEN, Z., PAN, Q., YANG, W., CHEN, Y., LI, X., AI, W., & GUO, S. (2019). 1859-P: Autophagy Promotes Gluconeogenesis in Hepatocytes through Forkhead/winged Helix Transcription Factor (FoxO1) Biosynthesis by Supporting Intracellular Amino Acids Turnover. Diabetes, 68(Supplement_1).
YANG, W., AI, W., LI, X., PAN, Q., SHEN, Z., CHEN, Y., ... & GUO, S. (2019). 1864-P: p38α MAPK Mediates Glucagon-Induced Hepatic Glucose Production through Phosphorylation of Foxo1 at Ser273. Diabetes, 68(Supplement_1).
Pan, Q., Chen, Y., Kim, D. M., Shen, Z., Yang, W., Li, X., ... & Guo, S. (2019). 1853-P: Transforming Growth Factor Beta 1 Acts as a Hepatokine in Control of Glucose and Energy Metabolism. Diabetes, 68(Supplement_1).
Kim, D. M., Lee, J. H., Pan, Q., Noh, J. Y., Wang, H., Han, H. W., ... & Sun, Y. (2019). 1989-P: Ablation of Ghrelin Receptor in Myeloid Cells Attenuates Diet-Induced NAFLD in Mice. Diabetes, 68(Supplement_1).
Yang, W., Yan, H., Pan, Q., Shen, J. Z., Zhou, F., Wu, C., ... & Guo, S. (2019). Glucagon regulates hepatic mitochondrial function and biogenesis through FOXO1. Journal of Endocrinology, 241(3), 265-278.
Zhang, K., Guo, X., Yan, H., Wu, Y., Pan, Q., Shen, J. Z., ... & Guo, S. (2019). Phosphorylation of forkhead protein FoxO1 at S253 regulates glucose homeostasis in mice. Endocrinology, 160(5), 1333-1347.
Li, X., Chen, Y., Shen, J. Z., Pan, Q., Yang, W., Yan, H., ... & Guo, S. (2019). Epigallocatechin gallate inhibits hepatic glucose production in primary hepatocytes via downregulating PKA signaling pathways and transcriptional factor FoxO1. Journal of agricultural and food chemistry, 67(13), 3651-3661.
Yan, H., Yang, W., Zhou, F., Li, X., Pan, Q., Shen, Z., ... & Guo, S. (2019). Estrogen improves insulin sensitivity and suppresses gluconeogenesis via the transcription factor Foxo1. Diabetes, 68(2), 291-304.
Liu, H., Liu, M., Jin, Z., Yaqoob, S., Zheng, M., Cai, D., ... & Guo, S. (2019). Ginsenoside Rg2 inhibits adipogenesis in 3T3-L1 preadipocytes and suppresses obesity in high-fat-diet-induced obese mice through the AMPK pathway. Food & Function, 10(6), 3603-3614.
2018
Xu, H., Li, X., Adams, H., Kubena, K., & Guo, S. (2018). Etiology of metabolic syndrome and dietary intervention. International journal of molecular sciences, 20(1), 128.
Liao, X., Song, L., Zeng, B., Liu, B., Qiu, Y., Qu, H., ... & Zheng, H. (2019). Alteration of gut microbiota induced by DPP-4i treatment improves glucose homeostasis. EBioMedicine, 44, 665-674.
Wu, Q., & Zheng, R. (Eds.). (2018). Neural regulation of metabolism. Springer Singapore.
Wu, Y., Pan, Q., Yan, H., Zhang, K., Guo, X., Xu, Z., ... & Guo, S. (2018). Novel mechanism of Foxo1 phosphorylation in glucagon signaling in control of glucose homeostasis. Diabetes, 67(11), 2167-2182.
Li, X., Liao, M., Shen, R., Zhang, L., Hu, H., Wu, J., ... & Zheng, H. (2018). Plasma asprosin levels are associated with glucose metabolism, lipid, and sex hormone profiles in females with metabolic-related diseases. Mediators of inflammation, 2018.
Wu, Y., Yan, H., Pan, Q., Zheng, H., Dahanayaka, S. A., Sun, Y., ... & Guo, S. (2018). A Novel Mechanism by Foxo1 Phosphorylation Mediates Glucagon Signaling in Control of Glucose Homeostasis. Diabetes, 67(Supplement_1).
Cai, Y., Li, H., Liu, M., Pei, Y., Zheng, J., Zhou, J., ... & Wu, C. (2018). Disruption of adenosine 2A receptor exacerbates NAFLD through increasing inflammatory responses and SREBP1c activity. Hepatology, 68(1), 48-61.
Yan, H., Wu, Y., Pan, Q., Shen, Z., Zheng, H., White, M. F., ... & Guo, S. (2018). Foxo1-Ser253 Phosphorylation Regulates Glucose Homeostasis in Mice. Diabetes, 67(Supplement_1).
Yang, W., Yan, H., Pan, Q., Shen, Z., Dahanayaka, S. A., Wu, C., ... & Guo, S. (2018). Glucagon Regulates Hepatic Mitochondrial Biogenesis and Function through Foxo1. Diabetes, 67(Supplement_1).
Yan, H., Zhou, F., Yang, W., Pan, Q., Shen, Z., Han, G., ... & Guo, S. (2018). Estrogen Improves Insulin Sensitivity and Suppresses Hepatic Glucose Production via the Transcription Factor Foxo1. Diabetes, 67(Supplement_1).
Pan, Q., Chen, Y., Yan, H., Yang, W., Shen, Z., Dahanayaka, S. A., & Guo, S. (2018). Regulation of hepatic glucose production by transforming growth factor beta 1 via protein kinase A. Diabetes, 67(Supplement_1).
Chen, J., Zhong, L., Wu, J., Ke, S., Morpurgo, B., Golovko, A., ... & Tian, Y. (2018). A murine pancreatic islet cell-based screening for diabetogenic environmental chemicals. JoVE (Journal of Visualized Experiments), (136), e57327.
Zhang, H., Shi, J. H., Jiang, H., Wang, K., Lu, J. Y., Jiang, X., ... & Zhang, W. J. (2018). ZBTB20 regulates EGFR expression and hepatocyte proliferation in mouse liver regeneration. Cell Death & Disease, 9(5), 462.
Yu, X., Guo, S., & Han, G. (2018). Echocardiographic assessment of G‐protein coupled estrogen receptor (GPER) activation on coronary blood flow and cardiac function in mice. The FASEB Journal, 32, 579-10.
Long, M., Cai, L., Li, W., Zhang, L., Guo, S., Zhang, R., ... & Zheng, H. (2018). DPP-4 inhibitors improve diabetic wound healing via direct and indirect promotion of epithelial-mesenchymal transition and reduction of scarring. Diabetes, 67(3), 518-531.
Fang, C., Xu, H., Guo, S., Mertens-Talcott, S. U., & Sun, Y. (2018). Ghrelin signaling in immunometabolism and inflamm-aging. Neural Regulation of Metabolism, 165-182.
2017
Cao, J., Peng, J., An, H., He, Q., Boronina, T., Guo, S., ... & He, L. (2017). Endotoxemia-mediated activation of acetyltransferase P300 impairs insulin signaling in obesity. Nature Communications, 8(1), 131.
Ganugula, R., Arora, M., Jaisamut, P., Wiwattanapatapee, R., Jørgensen, H. G., Venkatpurwar, V. P., ... & Majeti, N. V. R. K. (2017). Nano‐curcumin safely prevents streptozotocin‐induced inflammation and apoptosis in pancreatic beta cells for effective management of Type 1 diabetes mellitus. British journal of pharmacology, 174(13), 2074-2084.
Lin, L., Wu, C., Lee, J., Xu, A., Xu, Y., & Sun, Y. (2017). Ghrelin receptor deletion in AgRP neurons mitigates diet-induced obesity by activating thermogenesis.
Guo, C. A., & Guo, S. (2017). Insulin receptor substrate signaling controls cardiac energy metabolism and heart failure. The Journal of endocrinology, 233(3), R131.
Wu, Y., Long, Q., Xu, Y., Guo, S., Chen, T., Wang, L., ... & Walker, B. (2017). A structural and functional analogue of a Bowman–Birk-type protease inhibitor from Odorrana schmackeri. Bioscience reports, 37(2), BSR20160593.
Pradhan, G., Wu, C. S., Han Lee, J., Kanikarla, P., Guo, S., Yechoor, V. K., ... & Sun, Y. (2017). Obestatin stimulates glucose-induced insulin secretion through ghrelin receptor GHS-R. Scientific reports, 7(1), 979.
Wu, C. S., Bongmba, O. Y., Yue, J., Lee, J. H., Lin, L., Saito, K., ... & Sun, Y. (2017). Suppression of GHS-R in AgRP neurons mitigates diet-induced obesity by activating thermogenesis. International journal of molecular sciences, 18(4), 832.
2016
Xiang, J., Wang, H., Ma, C., Zhou, M., Wu, Y., Wang, L., ... & Shaw, C. (2016). Ex vivo smooth muscle pharmacological effects of a novel bradykinin-related peptide, and its analogue, from Chinese large odorous frog, Odorrana livida skin secretions. Toxins, 8(10), 283.
Wang, M., Luo, L., Yao, L., Wang, C., Jiang, K., Liu, X., ... & Yang, Y. (2016). Salidroside improves glucose homeostasis in obese mice by repressing inflammation in white adipose tissues and improving leptin sensitivity in hypothalamus. Scientific Reports, 6(1), 25399.
Drosatos, K., Pollak, N. M., Pol, C. J., Ntziachristos, P., Willecke, F., Valenti, M. C., ... & Goldberg, I. J. (2016). Cardiac myocyte KLF5 regulates Ppara expression and cardiac function. Circulation research, 118(2), 241-253.
Qi, Y., Guo, X., Guo, S., & Ahima, R. (2016). Insulin resistance in obesity. Metabolic Syndrome: A Comphensive Textbook. Cham, Switzerland: Springer International, 479-504.
2015
Qi, Y., Zhu, Q., Zhang, K., Thomas, C., Wu, Y., Kumar, R., ... & Guo, S. (2015). Activation of Foxo1 by insulin resistance promotes cardiac dysfunction and β–myosin heavy chain gene expression. Circulation: Heart Failure, 8(1), 198-208.
Wu, Y., Xu, Z., Li, L., Zhang, K., Qi, Y., & Guo, S. (2015, June). Regulation of Forkhead Transcription Factor FoxO1 by Protein Kinase A in Glucagon Signaling. In Diabetes (Vol. 64, pp. A86-A86). 1701 N BEAUREGARD ST, ALEXANDRIA, VA 22311-1717 USA: AMER DIABETES ASSOC.
Xie, W., Wang, L., Dai, Q., Yu, H., He, X., Xiong, J., ... & Zhang, K. (2015). Activation of AMPK restricts coxsackievirus B3 replication by inhibiting lipid accumulation. Journal of molecular and cellular cardiology, 85, 155-167.
2014
Qi, Y., Zhang, K., Wu, Y., Xu, Z., Yong, Q. C., Kumar, R., ... & Guo, S. (2014). Novel mechanism of blood pressure regulation by Forkhead box class O1–Mediated transcriptional control of hepatic angiotensinogen. Hypertension, 64(5), 1131-1140.
Ryu, J., Galan, A. K., Xin, X., Dong, F., Abdul-Ghani, M. A., Zhou, L., ... & Dong, L. Q. (2014). APPL1 potentiates insulin sensitivity by facilitating the binding of IRS1/2 to the insulin receptor. Cell reports, 7(4), 1227-1238.
Zhang, L., He, S., Guo, S., Xie, W., Xin, R., Yu, H., ... & Zhang, K. (2014). Down-regulation of miR-34a alleviates mesangial proliferation in vitro and glomerular hypertrophy in early diabetic nephropathy mice by targeting GAS1. Journal of Diabetes and its Complications, 28(3), 259-264.
Guo, S. (2014). Decoding insulin resistance and metabolic syndrome for promising therapeutic intervention. Journal of Endocrinology, 220(2), E1-E3.
Guo, S. (2014). Insulin signaling, resistance, and the metabolic syndrome: insights from mouse models to disease mechanisms. The Journal of endocrinology, 220(2), T1.
Ma, J., Zhang, L., Tipton, A. R., Wu, J., Messmer-Blust, A. F., Philbrick, M. J., ... & Guo, S. (2014). Structural and functional analysis of the related transcriptional enhancer factor-1 and NF-κB interaction. American Journal of Physiology-Heart and Circulatory Physiology, 306(2), H233-H242.
Guo, S. D. (2014). Tissue-specific insulin resistance and its associated mechanisms for metabolic syndrome. Journal of Third Military Medical University, 36(15), 1535-1542.
Guo, S. (2014). Mechanisms of Heart Failure in Type 2 Diabetes Mellitus. Austin journal of clinical cardiology, 1(1).
Yu, H., He, X., Xie, W., Xiong, J., Sheng, H., Guo, S., ... & Zhang, K. (2014). Elastase LasB of Pseudomonas aeruginosa promotes biofilm formation partly through rhamnolipid-mediated regulation. Canadian journal of microbiology, 60(4), 227-235.
2013
Qi, Y., Xu, Z., Zhu, Q., Thomas, C., Kumar, R., Feng, H., ... & Guo, S. (2013). Myocardial loss of IRS1 and IRS2 causes heart failure and is controlled by p38α MAPK during insulin resistance. Diabetes, 62(11), 3887-3900.
Guo, S., Qi, Y., Zhu, Q., Xu, Z., Thomas, C., Kumar, R., ... & Baker, K. (2013). Insulin Resistance and Mechanisms of Heart Failure.
Li, X., Long, D., Ji, J., Yang, W., Zeng, Z., Guo, S., ... & Chen, S. (2013). Sample preparation for the metabolomics investigation of poly-gamma-glutamate-producing Bacillus licheniformis by GC–MS. Journal of microbiological methods, 94(1), 61-67.
Zhang, K., Xu, Z., Qi, Y., Li, L., Zhu, Q., & Guo, S. (2013, July). Foxo1 Inhibits Hepatic Lipogenesis Involving Its Ser253 Dephosphorylation and Activation of AMPK. In DIABETES (Vol. 62, pp. A461-A461). 1701 N BEAUREGARD ST, ALEXANDRIA, VA 22311-1717 USA: AMER DIABETES ASSOC.
Guo, S. (2013). Molecular basis of insulin resistance: the role of IRS and Foxo1 in the control of diabetes mellitus and its complications. Drug Discovery Today: Disease Mechanisms, 10(1-2), e27-e33.
Qi, Y., Dostal, D., & Guo, S. (2013). Myocardial Activation of p38 alpha MAPK Results in Cardiac Insulin Resistance by Chronic Insulin Signaling.
Li, J., & Guo, S. (2013). Structural and Functional Analysis of the Related Transcriptional Enhancer 1 Factor-1 (RTEF-1) and Nuclear Factor Kappa B (NF-κB) Interaction 2.
2012
Zhang, K., Li, L., Qi, Y., Zhu, X., Gan, B., DePinho, R. A., ... & Guo, S. (2012). Hepatic suppression of Foxo1 and Foxo3 causes hypoglycemia and hyperlipidemia in mice. Endocrinology, 153(2), 631-646.
Zhang, K., Xu, Z., Qi, Y., Li, L., & Guo, S. (2012, June). Forkhead/Helix Transcription Factor Foxo1 Serine 253 Controls Nutrient Homeostasis in Mice. In DIABETES (Vol. 61, pp. A422-A422). 1701 N BEAUREGARD ST, ALEXANDRIA, VA 22311-1717 USA: AMER DIABETES ASSOC.
Messmer-Blust, A. F., Philbrick, M. J., Guo, S., Wu, J., He, P., Guo, S., & Li, J. (2012). RTEF-1 attenuates blood glucose levels by regulating insulin-like growth factor binding protein-1 in the endothelium. Circulation research, 111(8), 991-1001.
2011
Messmer-Blust, A. F., Wu, J., Jin, Y., Guo, S., & Li, J. (2011). Abstract P253: Transcriptional Regulation of the IGFBP-1 Gene by RTEF-1 in Endothelial Cells.
2010
Cheng, Z., Guo, S., Copps, K., Dong, X., Kollipara, R., Depinho, R., & White, M. (2010, June). The Hepatic Lipid Metabolism in Irs1 and Irs2 Double Knockout Mice. In DIABETES (Vol. 59, pp. A407-A408). 1701 N BEAUREGARD ST, ALEXANDRIA, VA 22311-1717 USA: AMER DIABETES ASSOC.
Guo, S., Gan, B., & Depinho, R. A. (2010, June). Regulation of Nutrient Homeostasis by Forkhead FoxO Proteins in the Liver of Mice. In DIABETES (Vol. 59, pp. A13-A13). 1701 N BEAUREGARD ST, ALEXANDRIA, VA 22311-1717 USA: AMER DIABETES ASSOC.
2009
Guo, S., Copps, K. D., Dong, X., Park, S., Cheng, Z., Pocai, A., ... & White, M. F. (2009). The Irs1 branch of the insulin signaling cascade plays a dominant role in hepatic nutrient homeostasis. Molecular and cellular biology, 29(18), 5070-5083.
Cheng, Z., Guo, S., Copps, K., Dong, X., Kollipara, R., Rodgers, J. T., ... & White, M. F. (2009). Foxo1 integrates insulin signaling with mitochondrial function in the liver. Nature medicine, 15(11), 1307-1311.
2008
Dong, X. C., Copps, K. D., Guo, S., Li, Y., Kollipara, R., DePinho, R. A., & White, M. F. (2008). Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation. Cell metabolism, 8(1), 65-76.
2006
Zhang, W., Patil, S., Chauhan, B., Guo, S., Powell, D. R., Le, J., ... & Unterman, T. G. (2006). FoxO1 regulates multiple metabolic pathways in the liver: effects on gluconeogenic, glycolytic, and lipogenic gene expression. Journal of Biological Chemistry, 281(15), 10105-10117.
Copps, K., Guo, S., & White, M. F. (2006, June). Insulin receptor substrate 1 (IRS1) serine 307-> Alanine (S307A) knock-in mice are insulin resistant. In Diabetes (Vol. 55, pp. A70-A71). 1701 N BEAUREGARD ST, ALEXANDRIA, VA 22311-1717 USA: AMER DIABETES ASSOC.
Guo, S., & White, M. F. (2006, June). Irs2 is the major regulator of p110a-> Akt-> Foxo1 signaling in mouse embryo fibroblasts. In DIABETES (Vol. 55, pp. A299-A300). 1701 N BEAUREGARD ST, ALEXANDRIA, VA 22311-1717 USA: AMER DIABETES ASSOC.
Guo, S., Dunn, S. L., & White, M. F. (2006). The reciprocal stability of FOXO1 and IRS2 creates a regulatory circuit that controls insulin signaling. Molecular endocrinology, 20(12), 3389-3399.
2005
Kushner, J. A., Simpson, L., Wartschow, L. M., Guo, S., Rankin, M. M., Parsons, R., & White, M. F. (2005). Phosphatase and tensin homolog regulation of islet growth and glucose homeostasis. Journal of Biological Chemistry, 280(47), 39388-39393.